Released on: May 19, 2008, 10:41 pm

Press Release Author: Belinda De Leon / Trevigen, Inc.

Industry: Biotech

Press Release Summary: Trevigen releases the first standardized kit for isolating
cells from 3-D Culture for biochemical analysis. The Cultrex® 3-D Culture Cell
Haversting Kit is based on a nonenzymatic approach which prevents biochemical
degradation during processing and overcomes the problems associated with extracting
cells from BME or Laminin I in 3-D Culture.

Press Release Body: Many scientists are converting from growing cells in a
traditional 2-D monolayer on plastic surfaces with tissue culture medium to "3-D"
Culture. In 3-D Culture, cells are grown in a microenvironment of specialized
proteins which mimics in vivo conditions and allows the cells to organize into
complexstructures rather than uniform monolayers. Further, 3-D Cultures are grown on
extracellular matrix proteins such as basement membrane extract and laminin I, which
are known to play a role in modulating cellular response to pharmacological
compounds. Until now, methods to remove cells from these 3-D models have either been
inefficient or resulted in the degradation of extracellular receptors which
adversely affects biochemical analysis.

Trevigen solves these problems with the release of the the first standardized kit
for isolating cells from 3-D Culture for biochemical analysis. The Cultrex® 3-D
Culture Cell Haversting Kit is based on a nonenzymatic approach which prevents
biochemical degradation during processing and overcomes the problems associated with
extracting cells from BME or Laminin I in 3-D Culture. The quality of the harvested
cells is ideal for western blotting, RNA and DNA analysis.

Trevigen, Inc. is a rapidly growing biotechnology company focused on the development
of products and technology for cancer research, emphasizing apoptosis, DNA damage
and repair, and cancer cell function and behavior. Trevigen has been a long-standing
provider of quality reagents and kits for researchers investigating programmed cell
death and DNA damage and repair. A logical extension of the focus on cancer research
has been the recent development of assays for cancer cell function and behavior
including angiogenesis, cell invasion and tumor formation. Currently, the product
portfolio contains over 500 products categorized into four processes - Apoptosis,
DNA Damage and Repair, Angiogenesis, and Oxidative Stress.

3-D qualified BME, Laminin I and Collagen I, as well as 3-D cell proliferation kits
are also available separately from Trevigen. Visit www.trevigen.com or contact us at
1800-873-8443 or info@trevigen.com for more information.


Web Site: http://www.trevigen.com

Contact Details: Trevigen, Inc.
8405 Helgerman Court
Gaitherburg, MD 20877
www.trevigen.com
info@trevigen.com
1-800-TREVIGEN